Suppressive valacyclovir therapy to reduce genital herpes transmission: Good public health policy?
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چکیده
منابع مشابه
Suppressive valacyclovir therapy to reduce genital herpes transmission: Good public health policy?
Nocturnal asthma (NA) is increasing in prevalence, affecting millions of people Genital herpes is a widespread sexually transmitted infection caused by the herpes simplex viruses (HSV). Suppressive valacyclovir therapy has been shown to significantly reduce HSV transmission. The benefits and costs of using valacyclovir to reduce transmission in couples discordant for genital herpes will be anal...
متن کاملValacyclovir to reduce transmission of genital herpes simplex virus infection.
fallacy. Am J Epidemiol 1988; 127:893–904. 3. Greenland S, Robins J. Invited commentary: ecologic studies–biases, misconceptions, and counterexamples. Am J Epidemiol 1994; 139: 747–60. 4. Blaser MJ, Chen Y, Reibman J. Does Helicobacter pylori protect against asthma and allergy? Gut 2008; 57:561–7. 5. Höök-Nikanne J, Pérez-Pérez GI, Blaser MJ. Antigenic characterization of Helicobacter pylori st...
متن کاملImpact of suppressive antiviral therapy on the health related quality of life of patients with recurrent genital herpes infection.
OBJECTIVE To investigate whether suppressive antiviral therapy improves health related quality of life in patients with recurrent genital herpes. METHODS Health related quality of life was measured using the disease specific recurrent genital herpes quality of life questionnaire (RGHQoL) as part of a randomized, double blind, 52 week, placebo controlled, dose ranging study of once and twice d...
متن کاملAdherence in HIV type 1 prevention trials.
Herpes simplex virus type 2 (HSV-2), the principal cause of genital herpes, infects the majority of human immunodeficien-cy virus type 1 (HIV-1)–infected persons worldwide [1]. HIV-1 is shed at high titers in genital ulcers caused by HSV-2 [2], and genital ulcer disease (GUD) increases the risk of HIV-1 transmission [3]. Asymp-tomatic HSV-2 reactivation (ie, viral shedding in the absence of gen...
متن کاملValacyclovir and acyclovir for suppression of shedding of herpes simplex virus in the genital tract.
BACKGROUND Valacyclovir exhibits better oral absorption and higher, more prolonged serum concentrations than oral acyclovir. The efficacy of valacyclovir and acyclovir on genital herpes simplex virus (HSV) shedding was assessed in a double-blind, 3-period crossover trial. METHODS Sixty-nine immunocompetent participants with genital HSV-2 received oral valacyclovir, acyclovir, and matching pla...
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ژورنال
عنوان ژورنال: McGill Journal of Medicine
سال: 2020
ISSN: 1715-8125
DOI: 10.26443/mjm.v12i1.732